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Toxicity study in naïve mice-The Federal Agency for Disruptive Innovation - SPRIND GmbH ("SPRIND") - aims to cre-ate new disruptive innovations from Germany. That means products, services and sys-tems that make all our lives noticeably and sustainably better. To achieve this, SPRIND brings together new thinkers from science and business, people with outstanding ideas, special expertise, and passion. Hence, SPRIND provides an entrepreneurial environment that turns ideas into reality. The objective of BiconY Therapeutics GmbH, a SPRIND subsidiary, is the development of a bispecific antibody combination for the treatment of solid tumours. The combination con-sists of proprietary, bispecific CD3 anti-bodies (bsAbCD3) and bispecific CD28 co-stimulators (BiCos), which, when used together, significantly im-prove the specificity, sus-tainability, and efficiency of a T cell recruitment and thus the immune response against tumour cells. The aim of the research and development activities is to provide proof of concept for the effect of bispecific antibody therapy in the form of two phase I/IIa clinical trials. For the IND application at Paul Ehrlich Institute (Germany) we have to show safety of our molecules in animal models. Following extensive discussions and thorough analyses, the PEI has granted approval for a comprehensive toxicological study of our lead candidate in mice. Therefore, we are looking for a service provider to support us regarding pharmaco-toxicological studies
Deutsches Evaluierungsinstitut der Entwicklungszusammenarbeit
Frist: 02. Oktober 2025
European Parliament
European Commission, DG REGIO - Regional and Urban Policy
European Union Agency for Asylum
Frist: 11. November 2025
European Commission, DG REGIO - Regional and Urban Policy
Frist: 08. Oktober 2025
Frist: 10. November 2025
Fraport AG
Frist: 24. Oktober 2025
Frist: 30. Oktober 2025
Deutsche Gesellschaft für Internationale Zusammenarbeit (GIZ) GmbH
Frist: 11. September 2025
European Innovation Council and SMEs Executive Agency
Frist: 20. Oktober 2025
European Parliament
Frist: 24. September 2025